Some years ago, I thought to help my daughter understand statistics by reanalyzing the data from a 2004 study on coffee and Parkinson’s disease mortality, “Coffee consumption, gender, and Parkinson’s disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen” , Am J Epidemiol. 2004 Nov 15;160(10):977-84, see it here
For the study, a cohort of over 1 million people was enrolled in 1982 and assessed for diet, smoking, alcohol, etc. Causes of deaths were ascertained through death certificates from January 1, 1989, through 1998. Death certificate data suggested that coffee decreased Parkinson’s mortality in men but not in women after adjustment for age, smoking, and alcohol intake. They used a technique I didn’t like though, ANOVA, analysis of variance. That is they compare the outcome of those who drank a lot of coffee (4 cups or more) to those who drank nothing. Though women in the coffee cohort had about 49% the death rate, it was not statistically significant by the ANOVA measure (p = 0.6). The authors of the study understood estrogen to be the reason for the difference.
I thought we could do a better by graphical analysis, see plot at right, especially using R2 to analyze the trend. According to this plot it appears that coffee significantly reduces the likelihood of death in both men and women, confidence better than 90%. Women don’t tend to drink as much coffee as men, but the relative effect per cup is stronger than in men, it appears, and the trend line is clearer too. In the ANOVA, it appears that the effect in women is small because women are less prone Parkinson’s.
There is a confounding behavior that I should note, it’s possible that people who begin to feel signs of Parkinson’s, etc. stop drinking coffee. I doubt it, give the study’s design, but it’s worth a mention. The same confounding is also present in a previous analysis I did that suggested that being overweight protected from dementia, and from Alzheimer’s. Maybe pre-dementia people start loosing weight long before other symptoms appear.
I have an apple tree, a peach tree, and some grape vines. They’re not big trees, but they give too much fruit to eat. The squirrels get some, and we give some away. As for the rest, I began making wine and apple jack a few years back, but there’s still more fruit than I can use. Being a chemical engineer, I decided to make brandy this year, so far only with pears and apples.
The first steps were the simplest: I collected fruit in a 5 gallon, Ace bucket, and mashed it using a 2×4. I then added some sugar and water and some yeast and let it sit with a cover for a week or two. Bread yeast worked fine for this, and gives a warm flavor, IMHO. A week or so later, I put the mush into a press I had fro grapes, shown below, and extracted the fermented juice. I used a cheesecloth bag with one squeezing, no bag with the other. The bag helped, making cleanup easier.
I did a second fermentation with both batches of fermented mash. This was done in a pot over a hot-plate on warm. I added more sugar and some more yeast and let it ferment for a few more days at about 78°F. To avoid bad yeasts, I washed out the pot and the ace bucket with dilute iodine before using them– I have lots of dilute iodine around from the COVID years. The product went into the aluminum “corn-cooker” shown above, 5 or 6 gallon size, that serves as the still boiler. The aluminum cover of the pot was drilled with a 1″ hole; I then screwed in a 10″ length of 3/4″ galvanized pipe, added a reducing elbow, and screwed that into a flat-plate heat exchanger, shown below. The heat exchanger serves as the condenser, while the 3/4″ pipe is like the cap on a moonshiner still. Its purpose is to keep the foam and splatter from getting in the condenser.
I put the pot on the propane burner stand shown, sealed the lid with masking tape (it worked better than duct tape), hooked up the heat exchanger to a water flow, and started cooking. If you don’t feel like making a still this way, you can buy one at Home Depot for about $150. Whatever route you go, get a good heat exchanger/ condenser. The one on the Home-depot still looks awful. You need to be able to take heat out as fast as the fire puts heat in, and you’ll need minimal pressure drop or the lid won’t seal. The Home Depot still has too little area and too much back-pressure, IMHO. Also, get a good thermometer and put it in the head-space of the pot. I used a thermocouple. Temperature is the only reasonable way to keep track of the progress and avoid toxic distillate.
The extra weight of the heat exchanger and pipe helps hold the lid down, by the way, but it would not be enough if there was a lot of back pressure in the heat exchanger-condenser. If your lid doesn’t seal, you’ll lose your product. If you have problems, get a better heat exchanger. I made sure that the distillate flows down as it condenses. Up-flow adds back pressure and reduces condenser efficiency. I cooled the condenser with water circulated to a bucket with the cooling water flowing up, counter current to the distillate flow. I could have used tap water via a hose with proper fittings for cooling, but was afraid of major leaks all over the floor.
With the system shown, and the propane on high, it took about 20 minutes to raise the temperature to near boiling. To avoid splatter, I turned down the heater as the temperature approached 150°F. The first distillate came out at 165°F, a temperature that indicated it was not alcohol or anything you’d want to drink. I threw away the first 2-3 oz of this product. You can sniff or sip a tiny amount to convince yourself that this this is really nasty, acetone, I suspect, plus ethyl acetate, and maybe some ether and methanol. Throw it away!
After the first 2-3 ounces, I collected everything to 211°F. Product started coming in earnest at about 172°F. I ended distillation at 211°F when I’d collected nearly 3 quarts. For my first run, my electronic thermometer was off and I stopped too early — you need a good thermometer. The material I collected and was OK in taste, especially when diluted a bit. To test the strength, I set some on fire, the classic “100% proof test”, and diluted till it to about 70% beyond. This is 70% proof, by the classic method. I also tried a refractometer, comparing the results to whiskey. I was aiming for 60-80 proof (30-40%).
I tried distilling a second time to improve the flavor. The result was stronger, but much worse tasting with a loss of fruit flavor. By contrast, a much better resulted from putting some distillate (one pass) in an oak barrel we had used for wine. Just one day in the barrel helped a lot. I’ve also seen success putting charred wood cubes set into a glass bottle of distillate. Note: my barrel, as purchased, had leaks. I sealed them with wood glue before use.
I only looked up distilling law after my runs. It varies state to state. In Michigan, making spirits for consumption, either 1 gal or 60,000 gal/year, requires a “Distilling, Rectifying, Blending and/or Bottling Spirits” Permit, from the ATF Tax and Trade Bureau (“TTB”) plus a Small Distiller license from Michigan. Based on the sale of stills at Home Depot and a call to the ATF, it appears there is little interest in pursuing home distillers who do not sell, despite the activity being illegal. This appears similar to state of affairs with personal use marijuana growers in the state. Your state’s laws may be different, and your revenuers may be more enthusiastic. If you decide to distill, here’s some music, the Dukes of Hazard theme song.
Elite colleges strive to be selective, and they are, just not for the hard-working scholars they claim to select for. They claim to be color-blind, income-blind, and race-blind, aiming for the best: the most intelligent, most ethical, and hardest working scholar-candidates. Then, to their surprise and satisfaction, all the ivies find that the vast majority of the chosen come from the same rich families and prep-schools as 100 years ago. That happens because the selection is crooked with measures tilted to the rich, Protestant, and preppy.
Through most of the 1900s, most of the ivies had a Jewish quota, enforced formally or informally. They also did their best to discourage middle class, black, and Catholic students in the interest of maintaining the proper student mix. Under Woodrow Wilson, Princeton went further and admitted not one black student. When quotas became illegal, schools began to rely on athletics and tests, with blatant cheating as revealed by the “Varsity Blues” sting operation. In that sting, a dozen or more athletic coaches and high-school administrators were caught taking SAT tests for their richer, connected students, and/or making up phony athletic achievements. The Ivies claimed shock after the cheating was revealed, but it is beyond belief that no one had noticed that these top brains and athletes were neither.
Another version of this is that richer kids can get extra time to do SAT and ACT tests. The extra time doesn’t show up on the SAT or ACT score, you need a doctor to certify that you are dyslectic or have severe ADHD. Most boys are diagnosed with ADHD these days, itself something of a scam, but most boys don’t get extra test time. You need the right doctor and the right documentation, plus enough money and connections to get the test given by certified test-giver in your own private room. It used to be that the SAT and ACT would report the extra time, but this changed in 2004. Now the extra time, and the disease is not documented, just the higher score. There have been complaints, but the scam goes on. Similar to this, top Olympic athletes can be diagnosed with asthma, and allowed to use performance enhancing, anti-asthma steroids. Again complaints, but no change.
Ivy League schools also tilt to the right families by requiring signs of the right sort of leadership as evaluated by an interview and an essay (see my post on John Kennedy’s essay). You score high on leadership if you helped your relative run for governor. By contrast, if you organized a ping-pong or basketball tournament at your Catholic or Jewish school, you’re the wrong sort of leader. Eagle Scout is sort-of the right sort, and speaking against climate change on TV is. Greta Thernberg and Chelsea Clinton are climate leaders; you, probably are not.
The Ivys explicitly state that they choose for athleticism, but not all sports are equal. All the Ivies claim to need a good women’s lacrosse team, a good crew team, and some good high-divers. Are these sports unavailable at your high-school? What a shame, you’re not a real athlete. You can still try to get in based on extreme leadership and academics.
There is no real reason that Harvard needs a top crew team, or needs to excel at women’s lacrosse or high-diving. Sport was not an admission criteria in the 1800s. It was added in the 1900s to avoid admitting Catholics, Jews, and Asians who tended to score well but could not compete on the selected sports. The president of Harvard, Abbot Lowell wrote, “Somehow or other the enrollment of the Jewish students must be limited”. The method he chose, and that all the Ivies came to use, included these tests of leadership and sport, plus a preference for legacies. The children and grand-children of alumni are given significant preferential selection at all the ivies. At Harvard, the acceptance rate for legacy students is about 33%, compared with an overall acceptance rate of under 6%. Since legacies are mostly white, rich, protestant, and preppy, the next generation is guaranteed to be the same.
The Ivies’ methods have been challenged many times over the years. Quotas were found to be illegal as early as 1964. Since then there have been claims of effective quotas, a cause that was pushed under the rug until Donal Trump took it up. Most recently, Harvard, Princeton, and UNC were sued by Asians. One of these, from a poor background scored at the top of his class with a 4.4 GPA and had near-perfect SAT scores, but was rejected for no obvious reason beyond race. The Supreme Court is expected to hear the case in 2023. Ahead of this decision, all eight Ivies have decided to dispense with testing for at least for now. The ivies claim that, by making tests optional, they will avoid locking out students who are great (though somewhat illiterate and innumerate). The real purpose seems to be to lock out pushy Asians who might sue them or be so bright they make the legacies feel dumb.
None of the above would matter if the Ivies were not so wonderful, at least the better ones are. I went to Princeton grad school, see photos. It was great despite its waspy leanings. If you can go there, or to Harvard, Yale, Cornell or Penn, go. My feeling for Brown and Columbia are rather the opposite: they’ve gone to the extreme and voted for BDS, see the text here for Brown’s version. Not only did they vote to boycott Israelis and Israeli produce, the “B” of BDS, the’ve also committed to suppress Zionists everywhere. That’s Jews who support Israel. Several, non ivy schools, have committed to the same. In their view, for open debate to flourish anywhere, proud Jews must be excluded. These are no longer colleges, but Klavens.
Sharrow Marine introduced a new ship propeller design two years ago, at the Miami International Boat show. Unlike traditional propellers, there are no ends on the blades. Instead, each blade is a connecting ribbon with the outer edge behaving like a connecting winglet. The blade pairs provide low-speed lift-efficiency gains, as seen on a biplane, while the winglets provide high speed gains. The efficiency gain is 9-30% over a wide range of speeds, as shown below, a tremendous improvement. I suspect that this design will become standard over the next 10-20 years, as winglets have become standard on airplanes today.
The high speed efficiency advantage of the closed ends of the blades, and of the curved up winglets on modern airplanes is based on avoiding losses from air (or water) going around the end from the high pressure bottom to the low-pressure top. Between the biplane advantage and the wingtip advantage, Sharrow propellers provide improved miles per gallon at every speed except the highest, 32+ mph, plus a drastic decrease in vibration and noise, see photo.
The propeller design was developed with paid research at the University of Michigan. It was clearly innovative and granted design patent protection in most of the developed world. To the extent that the patents are respected and protected by law, Sharrow should be able to recoup the cost of their research and development. They should make a profit too. As an inventor myself, I believe they deserve to recoup their costs and make a profit. Not all inventions lead to a great product. Besides, I don’t think they charge too much. The current price is $2000-$5000 per propeller for standard sizes, a price that seems reasonable, based on the price of a boat and the advantage of more speed, more range, plus less fuel use and less vibration. This year Sharrow formed an agreement with Yamaha to manufacture the propellers under license, so supply should not be an issue.
China tends to copy our best products, and often steals the technology to make them, employing engineers and academics as spys. Obama/Biden have typically allowed China to benefit for the sales of copies and the theft of intellectual property, allowing the import of fakes to the US with little or no interference. Would you like a fake Rolex or Fendi, you can buy on-line from China. Would you like fake Disney, ditto. So far, I have not seen Chinese copies of the Sharrow in the US, but I expect to see them soon. Perhaps Biden’s Justice Department will do something this time, but I doubt it. By our justice department turning a blind eye to copies, they rob our innovators, and rob American workers. His protectionism is one thing I liked about Donald Trump.
Eliquis (apixaban) is blood thinner shown to prevent stroke with fewer side effects than Warfarin (Coumadin). Aspirin does the same, but not as effectively for people over 75. My problem with eliquis is that it’s over-prescribed. The studies favoring it over aspirin found benefits for those over 75, and for those with A-Fib. And even in this cohort the advantage over aspirin is small or non-existent because eliquis has far more serious side effects; hemorrhage, or internal bleeding.
Statistically, the AVERROES study (Apixaban Versus Acetylsalicylic Acid to Prevent Stroke in AF Patients Who Have Failed or Are Unsuitable for Vitamin K Antagonist Treatment) found that apixaban is substantially better than aspirin at preventing stroke in atrial fibrillation patients, but worse at preventing heart attack.
Taking 50 mg of Eliquis twice a day, reduces the risk of stroke in people with A-Fib by more than 50% and reduces the rate of heart attack by about 15%. By comparison, taking 1/2 tablet of aspirin, 178 mg, reduces the risk of stroke by 17% and of heart attack by 42%. The benefits were higher in the elderly, those over 75, and non existent in those with A-Fib under 75, see here, and figure. Despite this, doctors prescribe Eliquis over aspirin, even to those without A-Fib and those under 75. I suspect the reason is advertising by the drug companies, as I’ve claimed earlier with Atenolol.
The major deadly side-effect is hemorrhage, brain hemorrhage and GI (stomach) hemorrhage. Here apixaban is far worse than with aspirin (but better than Warfarin). The net result is that in the AVERROES random-double blind study there was no difference in all-cause mortality between apixaban and aspirin for those with A-fib who were under 75, see here. Or here.
To reduce your chance of GI hemorrhage with Eliquis, it is a very good idea to take a stomach proton pump drug like Pantoprazole. If you have A-Fib, the combination of Eliquis and pantoprazole seems better than aspirin alone, even for those under 75. If you have no A-Fib and are under 75, I see no benefit to Eliquis, especially if you find you have headaches, stomach aches, back pain, or other signs of internal bleeding, you might switch to aspirin or choose a reduced dose.
A Japanese study found that half the normal dose of Eliquis, was approximately as effective as the full dose, 50 mg twice a day. I was prescribed Eliquis, full dose twice a day, but I’m under 70 and I have no A-Fib since my ablation.
I’m struck by the fact that US life expectancy is uncommonly low, lower than in most developed countries. Lower too than in many semi-developed countries, and our life expectancy is decreasing while other countries are not seeing the same. It dropped by about 3 years over the last 2 years as shown. I wonder why the US has suffered more than other countries, and suspect we are over-prescribed. Too much of a good thing, typically isn’t good.
Atenolol and related beta blockers have been found to be effective reducing blood pressure and heart rate. Since high blood pressure is a warning sign for heart problems, doctors have been prescribing atenolol and related beta blockers for all sorts of heart problems, even problems that are not caused by high blood pressure. I was prescribed metoprolol and then atenolol for Atrial Fibrillation, A-Fib, beginning 2 yeas ago, even though I have low-moderate blood pressure. For someone like me, it might have been deadly. Even for patients with moderately high blood pressure (hypertension) studies suggest there is no heart benefit to atenolol and related ß-blockers, and only minimal stroke and renal benefit. As early as 1985 (37 years ago) the Medical Research Council trial found that “ß blockers are relatively ineffective for primary treatment of hypertensive outcomes.”
There lots of adverse side-effects to atenolol, as listed at the end of this post. More recent studies (e.g. Carlsberg et al., at right) continue to find no positive effects on the heart, but lots of negatives. A review in Lancet (2004) 364,1684–9 was titled, “Review: atenolol may be ineffective for reducing cardiovascular morbidity or all cause mortality in hypertension” (link here). “In patients with essential hypertension, atenolol is not better than placebo or no treatment for reducing cardiovascular morbidity or all cause mortality.” It further concluded that, “compared to other antihypertensive drugs, it [atenolol] may increase the risk of stroke or death.” I showed this and related studies to my doctor, and pointed out that I have averaged to low blood pressure, but he persisted in pushing this drug, something that seems common among medical men. My guess is that the advertising or doctor subsidies are spectacular. By contrast, aspirin has long been known to be effective for heart problems; my doctor said to go off aspirin.
The graph at right is from “Trial of Secondary Prevention with Atenolol after transient Ischemic Attack or Nondisabling Ischemic Stroke”, published in Stroke, 24 4 (1993), (see link here). a Thje study involved 1473 at-risk patients, randomly prescribed atenolol or placebo. It found no outcome benefit from atenolol, and several negatives. After 3 years, in two equal-size randomized groups, there were 64 deaths among the atenolol group, 58 among the placebo group; there were 11 fatal strokes with atenolol, versus 8 with placebo. There were somewhat fewer non-fatal strokes with atenolol, but the sum-total of fatal and non-fatal strokes was equal; there were 81 in each group.
Newer beta blockers seem marginally better, as in “Effect of nebivolol or atenolol vs. placebo on cardiovascular health in subjects with borderline blood pressure: the EVIDENCE study.” “Nebivolol (NEB) in contrast to atenolol (ATE) may have a beneficial effect on endothelial function …. there was no significant change in the ATE and PLAC groups.” My question: why not use one of these, or better yet aspirin. Aspirin is shown to be beneficial, and relatively side-effect free. If you tolerate aspirin, and most people do, beneficial has to be better than maybe beneficial.
Among atenolol’s ugly side effects, as listed by the Mayo Clinic, there are: tiredness, sweating, shortness of breath, confusion, loss of sex drive, cold fingers and toes, diarrhea, nausea, and general confusion. I had some of these. There was no increase in heart stability (decrease in A-fib). My heart rate went as low at 32 bpm at night. My doctor was unconcerned, but I was. I suspected the low heart rate put me at extreme risk. Eventually, the same doctor gave me ablation therapy, and that seemed to cure the A-Fib.
Following my ablation, I was told I could get off atenolol. I then discovered another negative effect of atenolol: you have to ease off it or your heart will race. If you have A-fib, or modest hypertension, consider aspirin, eliquis, ablation, or exercise. If you are prescribed atenolol for heart issues and don’t have symptoms of very-high blood pressure, consider other options and/or changing doctors.
Two years ago, I was diagnosed with Atrial fibrillation, A-Fib in common parlance, a condition where my heart would sometimes speed up to double its normal speed. I was prescribed metopolol and then atenolol, common beta blockers, and a C-Pap for sleep apnea. None of this seemed to help, as best I could tell from occasional pulse measurements with watch and a finger pulse-oxometer. Besides, the C-Pap was giving me cough and the beta blockers made me dizzy. And the literature on C-Pap did not impress.
So, some moths ago, I bought an iWatch. The current versions allows you to take EKGs and provides a continuous record of your heart rate. This was very helpful, as I saw that my heart rate was transitioning to chaos. While it was normally predictable, it would zoom to 130 or so at some point virtually every day. Even more alarming, it would slow down to the mid 30s at some point during the night, bradycardia, and I could see it was getting worse. At that point, I agreed to go on eliquis, a blood thinner, and agreed to a catheter ablation. The doctor put a catheter into my heart by way of a leg vein, and zapped various nerve centers in the heart. The result is that my heart is back into normal behavior. See the heart-rate readout from my iWatch below; before and after are dramatically different.
The reason I chose ablation over drugs or no therapy was that I read health-studies on line. I’ve go a PhD, and that training helps me to understand the papers I’ve read, but you should read them too. They are not that hard to understand. Though ablation didn’t appear as a panacea, it was clearly better than the alternatives. Particularly relevant was the CABANA study on life expectancy. CABANA stands for “Catheter ABlation vs ANtiarrhythmic Drug Therapy for Atrial Fibrillation – CABANA”. https://www.acc.org/latest-in-cardiology/clinical-trials/2018/05/10/15/57/cabana.
2,204 individuals with persistent AF were followed for 5 years after treatment, 37% female, 63% male, average age 67.5. Prior hospitalization for AF: 39%. The results were as follows:
Death: 5.2% for ablation vs. 6.1% for drug therapy (p = 0.38)
Serious stroke: 0.3% for ablation vs. 0.6% for drug therapy (p = 0.19)
All-cause mortality: 4.4% for ablation vs. 7.5% for drug therapy (p = 0.005)
Death or CV hospitalization: 51.7% for ablation vs. 58.1% for drug therapy (p = 0.002)
Pericardial effusion with ablation: 3.0%; ablation-related events: 1.8%
First recurrent AF/atrial flutter/atrial tachycardia: 53.8% vs. 71.9% (p < 0.0001)
I found all of this significant, including the fact that 27.5% of those on the drug treatment crossed over to have ablation while only 9.2% on the ablation side crossed to have the drug treatment.
I must give a plug for doctor Ahmed at Beaumont Hospital who did the ablation. He does about 200 of these a year, and does them well. Do not go to an amateur. I was less-than impressed with him pushing the beta-blocker hard; I’ll write about that. Also, get an iWatch if you think you may have A-Fib or any other heart problem. You see a lot, just by watching, so to speak.
When I began college in 1972, the majority of engineering students and business students were male. They from the top of their high school classes, and from stable homes mostly; they went on to high paying jobs. Boys also dominated at the bottom of society. They were the majority of the criminals, drug addicts, and high-school dropouts. Many went off to Vietnam. Some, those who were handy, went to trade schools and a reasonable life, productive life. Society did not seem bothered by the destruction of boys in prison, or Vietnam, or by drugs, but there was an outcry that so few women achieved high academic levels. A famous presentation of the problem was called “for every 100 girls.” An updated version appears below showing the status as of October, 2021. A more detailed version appears further down.
From the table above, you can see that women are now the majority of those in college, the majority of those with a bachelors degree or higher, and a majority of those with advanced degrees. Colleges added special tutoring, special grants, and special programs. Each college had a Society of Women Engineers office, and similar programs in law and math. All of these explicitly excluded men or highly discouraged their presence. The curriculum was changed too; made more female-friendly. Dirty, and physical experiments were removed, replaced with group analysis of the social interactions — important aspects of engineers that boys were far-less adept at doing well. Perhaps society and engineering is better off now, but boys (men) are far worse off. This is particularly seem by the following chart, looking at the bottom. Boys/men provide the vast majority of the prison population, of those diagnosed as learning disabled, of those expelled, or overdosed, and among the war dead.
I’ve previously noted that a majority of boys in school are considered disruptive, and that these boys are routinely diagnosed as ADHD and drugged. It is not at all clear that this is a good thing, or that the drugs help anyone but the teacher. I’ve also noted that artwork and attitudes that were considered normal for boys are now considered disturbing and criminal like saying I wish the school was blown up. The cure here, perhaps is worse than the disease. I’m not saying that we should encourage boys to say such things, but that we should acknowledge a difference between an active and a passive wish. And we should find a way to educate boys/men so they don’t end up unemployed, addicted, or dead. Currently boy, particularly those at the bottom are on the scrap-heap of society.
Here is some source material for the above:
For every 100 women enrolled in US colleges (degree-granting postsecondary institutions) at all levels there are 75 men enrolled. Source: National Center for Education Statistics
For every 100 women enrolled in US graduate schools there are 68 men. Source: Council for Graduate Schools (2020)
For every 100 women who earn bachelor’s degrees from US colleges and universities, there are 73 men. Source: National Center for Education Statistics (2021-2022)
For every 100 females in local jails in the US, there are 614 males. Source: Department of Justice via Wikipedia
For every 100 females in state and federal prisons, there are 1,225 males. Source: Department of Justice
For every 100 females in federal prison, there are 1,331 male prisoners. Source: Federal Bureau of Prisons
For every 100 female military personnel who have been wounded in action during Operation Enduring Freedom, 5,098 men have. Source: Congressional Research Service
For every 100 female military personnel who have been wounded in action during Operation Iraqi Freedom, 4,982 menhave. Source: Congressional Research Service
I’m not sure why this is, but a quick look at the death statistics shows that it is no lower today than it was a year ago. Vaccines seem to help the individual, but they don’t seem to do much for society as a whole.
That the death rates are the same as last November is bad, especially since one major effect of COVID has been to wipe out nearly all our old folks, decreasing the lifespan of US men by 2-3 years. With a 70% vaccination rate (adults, 60% overall), and few old people, you ‘d expect our death rate this year would be lower than last.
Currently, at least, the trend-line looks positive, but that’s likely a mirage. It is common to add more deaths to the tally, retroactively a few weeks out as many deaths take weeks to report and more weeks to be counted as COVID. For what it’s worth, I’m vaccinated, two shots and a booster. I also take aspirin, and have gotten a pneumonia shot. I think it helps. What do I know?
As we discuss the effectiveness of the various COIVD vaccines, and ask if we will need another booster in a year, this time for the delta variant, or epsilon, it’s worth noticing that none of these is that deadly, especially if you’ve had a previous version. There are far worse viruses out there, like Ebola-Zaire, for example. This virus kills 60-90% of the people infected, typically by causing the body’s connective tissue to dissolve. Now that’s a deadly virus; imagine an ebola pandemic.
We live surrounded by many really deadly viruses, most of them incurable. In general our protection from them is that they usually show a slow infection rate or a slow progress to death. Drug resistant leprosy is one of these. Here’s the beginnings of a list of deadly viruses we could worry about: Lassa, Rift Vally, Oropouche, Rocio Q Guanarito, VEE, Marburg, Herpes B, Monkey Pox, Dengue, Chikunguanya, Hantavirus, Machupo, Junin, Rabies-like Mokola, drug-resistant leprosy, Duvenhage, LeDantec, Kyasanur, Forest Brain virus, HIV-AIDs, Simliki, Crimean-Congo virus, Sindbis, O’nyongnyong, Sao Paulo, SARS, Ebola Sudan, Ebola Zaire, Ebola Reston, Mid-East Respiratory (MERS), Zika, Delta-COVID. (I got 2/3 of this list from a 1993 book called “The Hot Zone” about the first US outbreak of Ebola — Washington DC in 1989 — a good book, worth a read).
As an ilk, these viruses are far older than we are, older than the first cellular creatures, and far tougher. They are neither dead nor alive, and can last for years generally without air, water or food if the temperature is right. Though they do not move on their own, nor eat in any normal sense, they do reproduce, and they do so with a vengeance. They also manage to evolve by an ingenious sexual mechanism. In a sense, they are the immune system of the earth, protecting the earth from man or any other invasive life form. We humans have only survived the virus for 100,000 years or so. Long term, the viruses are likely to win.
Some viruses are string shaped; Marburg and Ebola are examples. Such viruses can crystalize and live virtually forever on dry surfaces. Other viruses are ball-shaped, COVID and Zika, for example. These are more easily attacked on surfaces, e.g. by iodine. They become inactive after just a few minutes in air– and are killed instantly by iodine, alcohol, bleach, or peroxide.
Most viruses enter by cuts and body fluids. This is the case with AIDS and herpes. Others, like measles, shingles, and Zika, enter by way of surfaces and the hands. Virus-laden droplets collect on surfaces and are brought to a new host when the surface is touched and hand-transported to the nose or eyes. A few viruses, like SARS, Ebola, and COVID-19 can enter the body by breathing too. I’ve collected some evidence in favor of Iodine as a surface wipe, a hand wipe and as mouthwash in this previous essay.
Dr. Robert E. Buxbaum, November 3, 2021. The US has three facilities where they deal with the most deadly, contagious viruses. One is in Washington DC; they had leak in 1989, a part of the ebola outbreak. China has only one such facility, in Wuhan, China. It’s one block from where the COVID-19 outbreak supposedly originated. Have a nice day.